Data-sovereign, operator-reviewed discovery campaigns for antibody evolution and protein engineering. Each campaign starts from exact sequences, explicit biological constraints, and a prospective measurement plan; retains method-specific evidence and applicability limits; and records complete lineage and provenance in NextELN. Computational rankings are research hypotheses—not proof of expression, stability, binding, specificity, immunogenicity, safety, or efficacy. Scope and pricing are provided by quotation.