Lentivirus Pseudotyped with SARS-CoV-2 Spike Glycoprotein, HexaPro Stabilized Trimer

Catalog #: EG-341
$0.00
View Cart
Product Description
Product Name Lentivirus Pseudotyped with SARS-CoV-2 Spike Glycoprotein, HexaPro Variant
Catalog Number EG-341
Description Lentivirus particles pseudotyped with SARS-CoV-2 spike glycoprotein (Wuhan-Hu-1, GenBank: QHD43416.1), stabilized as a trimer (HexaPro variant) with mutations (RRAR682–685GSAS, F817P, A892P, A899P, A942P, K986P, V987P) to maintain an antigenically optimal prefusion conformation, produced in HEK293T cells and purified by ultracentrifugation, expressing EGFP as a reporter.
Mutations RRAR682–685GSAS, F817P, A892P, A899P, A942P, K986P, V987P
Source HEK293T cells
Reporter EGFP
Applications
  • Screening SARS-CoV-2 neutralizing antibodies
  • Assessing vaccine efficacy
Titer >1 × 107 RFU/mL or >1 × 105 TU/mL
Storage -80°C
Shipping Dry ice
References
  • Zost, S. J., et al. (2020). Effective screening of SARS-CoV-2 neutralizing antibodies in patient serum using lentivirus particles pseudotyped with SARS-CoV-2 spike glycoprotein. Scientific Reports, 10, 19076. doi:10.1038/s41598-020-76135-w.
  • Starr, T. N., et al. (2021). Prospective mapping of viral mutations that escape antibodies used to treat COVID-19. Science, 371(6531), 850–854. doi:10.1126/science.abf9302.
Related Products
Catalog #Product NamePriceAdd to Cart
EG-302SARS-Cov-2 Spike Glycoprotein Receptor Binding Domain, RBD (319-541), His tag0.00
EG-303SARS-CoV-2 Spike Glycoprotein, Stabilized Trimer, His tag0.00
EG-304SARS-CoV-2 Spike Glycoprotein D614G mutant, Stabilized Trimer, His tag0.00
EG-323SARS-CoV-2 Spike Glycoprotein RBD (319-541), South Africa Variant, His tag0.00
EG-324SARS-CoV-2 Spike Glycoprotein RBD (319-541), United Kingdom Variant, His tag0.00
EG-325SARS-CoV-2 Spike Glycoprotein, HexaPro Stabilized Trimer, His and Twin-Strep Tags0.00