Lentivirus Pseudotyped with SARS-CoV-2 Spike Glycoprotein, South Africa Variant

Catalog #: EG-342
$0.00
View Cart
Product Description
Product Name Lentivirus Pseudotyped with SARS-CoV-2 Spike Glycoprotein, HexaPro Variant, South African Variant
Catalog Number EG-342
Description Lentivirus particles pseudotyped with SARS-CoV-2 spike glycoprotein (Wuhan-Hu-1, GenBank: QHD43416.1, South African variant, B.1.351), stabilized as a trimer (HexaPro variant) with mutations (RRAR682–685GSAS, F817P, A892P, A899P, A942P, K986P, V987P, K417N, E484K, N501Y) to maintain an antigenically optimal prefusion conformation, produced in HEK293T cells, purified by ultracentrifugation, expressing EGFP as a reporter.
Mutations RRAR682–685GSAS, F817P, A892P, A899P, A942P, K986P, V987P, K417N, E484K, N501Y
Source HEK293T cells
Reporter EGFP
Applications
  • Screening SARS-CoV-2 neutralizing antibodies
  • Assessing vaccine efficacy
Titer >1 × 107 RFU/mL or >1 × 105 TU/mL
Storage -80°C
Shipping Dry ice
References
  • Zost, S. J., et al. (2020). Effective screening of SARS-CoV-2 neutralizing antibodies in patient serum using lentivirus particles pseudotyped with SARS-CoV-2 spike glycoprotein. Scientific Reports, 10, 19076. doi:10.1038/s41598-020-76135-w.
  • Starr, T. N., et al. (2021). Prospective mapping of viral mutations that escape antibodies used to treat COVID-19. Science, 371(6531), 850–854. doi:10.1126/science.abf9302.
Related Products
Catalog #Product NamePriceAdd to Cart
EG-302SARS-Cov-2 Spike Glycoprotein Receptor Binding Domain, RBD (319-541), His tag0.00
EG-303SARS-CoV-2 Spike Glycoprotein, Stabilized Trimer, His tag0.00
EG-304SARS-CoV-2 Spike Glycoprotein D614G mutant, Stabilized Trimer, His tag0.00
EG-323SARS-CoV-2 Spike Glycoprotein RBD (319-541), South Africa Variant, His tag0.00
EG-324SARS-CoV-2 Spike Glycoprotein RBD (319-541), United Kingdom Variant, His tag0.00
EG-325SARS-CoV-2 Spike Glycoprotein, HexaPro Stabilized Trimer, His and Twin-Strep Tags0.00