Human Angiotensin-Converting Enzyme 2 (ACE2) Lentivirus

Catalog #: EG-344
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Product Description
Product Name Human Angiotensin-Converting Enzyme 2 (ACE2) Lentivirus
Description Recombinant lentivirus expressing human angiotensin-converting enzyme 2 (ACE2), a key receptor for SARS-CoV-2 viral entry. Produced in HEK293T cells with EGFP reporter for transduction efficiency monitoring.
Source HEK293T cells
Reporter EGFP (enhanced green fluorescent protein)
Applications
  • Screening of SARS-CoV-2 neutralizing antibodies
  • Assessment of vaccine efficacy against ACE2-dependent variants
  • Studies of viral entry mechanisms and receptor utilization
Titer > 1 × 107 RFU/mL (relative fluorescence units) or > 1 × 105 TU/mL (transducing units)
Shipping Dry ice
Storage –80°C
References
  1. Effective screening of SARS-CoV-2 neutralizing antibodies in patient serum using lentivirus particles pseudotyped with SARS-CoV-2 spike glycoprotein. Sci Rep 10, 19076 (2020). doi:10.1038/s41598-020-76135-w
  2. Prospective mapping of viral mutations that escape antibodies used to treat COVID-19. Science 371(6531), 850-854 (2020). doi:10.1126/science.abf9302. PubMed: 33495308.
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