Murine Leukemia Virus (MLV) Pseudotyped with SARS-CoV-2 Spike Glycoprotein

Catalog #: EG-345

$0.00

Product Description

Product Name	Murine Leukemia Virus (MLV) Pseudotyped with SARS-CoV-2 Spike Glycoprotein, HexaPro Variant
Catalog Number	EG-345
Description	Murine leukemia virus (MLV) particles pseudotyped with SARS-CoV-2 spike glycoprotein (Wuhan-Hu-1, GenBank: QHD43416.1), stabilized as a trimer (HexaPro variant) with mutations (RRAR682–685GSAS, F817P, A892P, A899P, A942P, K986P, V987P) to maintain an antigenically optimal prefusion conformation, produced in HEK293T cells, purified by ultracentrifugation, expressing EGFP as a reporter.
Mutations	RRAR682–685GSAS, F817P, A892P, A899P, A942P, K986P, V987P
Source	HEK293T cells
Reporter	EGFP
Applications	Screening SARS-CoV-2 neutralizing antibodies Assessing vaccine efficacy
Titer	>1 × 10⁷ RFU/mL or >1 × 10⁵ TU/mL
Storage	-80°C
Shipping	Dry ice
References	Millet, J. K., & Whittaker, G. R. (2016). Murine leukemia virus (MLV)-based coronavirus spike-pseudotyped particle production and infection. Bio-Protocol, 6(23), e2035. doi:10.21769/BioProtoc.2035. Giroglou, T., et al. (2004). Retroviral vectors pseudotyped with severe acute respiratory syndrome coronavirus S protein. Journal of Virology, 78(17), 9007–9015. doi:10.1128/JVI.78.17.9007-9015.2004.

Product Documents

DatasheetEG-345 Product Datasheet

Related Products

Catalog #	Product Name	Price	Add to Cart
EG-302	SARS-Cov-2 Spike Glycoprotein Receptor Binding Domain, RBD (319-541), His tag	298.00
EG-303	SARS-CoV-2 Spike Glycoprotein, Stabilized Trimer, His tag	298.00
EG-304	SARS-CoV-2 Spike Glycoprotein D614G mutant, Stabilized Trimer, His tag	298.00
EG-323	SARS-CoV-2 Spike Glycoprotein RBD (319-541), South Africa Variant, His tag	298.00
EG-324	SARS-CoV-2 Spike Glycoprotein RBD (319-541), United Kingdom Variant, His tag	298.00
EG-325	SARS-CoV-2 Spike Glycoprotein, HexaPro Stabilized Trimer, His and Twin-Strep Tags	298.00

SARS-Cov-2 Spike Glycoprotein Receptor Binding Domain, RBD (319-541), His tag

Catalog #: EG-302$298.00

SARS-CoV-2 Spike Glycoprotein, Stabilized Trimer, His tag

Catalog #: EG-303$298.00

SARS-CoV-2 Spike Glycoprotein D614G mutant, Stabilized Trimer, His tag

Catalog #: EG-304$298.00

SARS-CoV-2 Spike Glycoprotein RBD (319-541), South Africa Variant, His tag

Catalog #: EG-323$298.00

SARS-CoV-2 Spike Glycoprotein RBD (319-541), United Kingdom Variant, His tag

Catalog #: EG-324$298.00

SARS-CoV-2 Spike Glycoprotein, HexaPro Stabilized Trimer, His and Twin-Strep Tags

Catalog #: EG-325$298.00