3D Structure — Nanobody–Epitope Complex
Loading 3D structure…
anti-PD-L1 nanobody complex
PDB 7CZD
■ nanobody (VHH) ■ antigen ■ epitope (53)
Drag to rotate · scroll to zoom
Interactive model of the VHH bound to its structural epitope on PD-L1 (from experimental complex PDB 7CZD). Nanobody in blue, epitope contact residues in red. For research visualization.
Product Description
| Product Name | Anti-PD-L1 Nanobody (VHH), Recombinant, Purified |
| Description | A purified, engineered VHH nanobody against human PD-L1 for immuno-oncology research. Compact and stable for tissue penetration and multiplexed imaging. |
| Target / Specificity | Human PD-L1 (CD274 / B7-H1) |
| Sequence | This nanobody is an engineered variant based on PDB 7CZD, with higher affinity and stability than the original published sequence. |
| Format | Purified recombinant single-domain antibody (VHH / nanobody), carrier-free |
| Tag & Expression | C-terminal 6×His tag; secreted from HEK293 cells and purified by one-step IMAC from the culture medium. |
| Molecular Weight | ~14 kDa (single VHH domain + His6; ~1/10 the size of a conventional IgG) |
| Purity | >90% by SDS-PAGE |
| Quantity | 100 µg |
| Formulation | PBS with 50% glycerol (carrier-free); 0.02% sodium azide |
| Applications | IF, flow cytometry, ELISA, checkpoint-ligand detection, immuno-oncology research |
| Structural Epitope | Epitope mapped from the experimental VHH–antigen complex (PDB 7CZD); 53 antigen contact residues within 5 Å. An interactive 3D complex model is shown on this page. |
| Storage | Store at -20°C; avoid repeated freeze-thaw. Stable 1 year. |
| Advantages | Nanobodies are the smallest functional antibody fragments: exceptional thermal and chemical stability, single-domain, high-yield recombinant production, and access to cryptic epitopes and dense tissue that conventional antibodies cannot reach. |
Product Documents
DatasheetEG-NB-PDL101 Product Datasheet
Download PDFRelated Products
Anti-GFP Nanobody (VHH), Recombinant, Purified
Catalog #: EG-NB-GFP01$355.00
Anti-RFP / mCherry Nanobody (VHH), Recombinant, Purified
Catalog #: EG-NB-RFP01$355.00
Anti-EGFR Nanobody (VHH), Recombinant, Purified
Catalog #: EG-NB-EGFR01$425.00
Anti-SARS-CoV-2 Spike Nanobody (VHH), Recombinant, Purified
Catalog #: EG-NB-SPK01$425.00
Anti-Influenza Hemagglutinin (HA) Nanobody (VHH), Recombinant, Purified
Catalog #: EG-NB-HA01$445.00
Anti-HIV-1 Envelope (gp120/gp160) Nanobody (VHH), Recombinant, Purified
Catalog #: EG-NB-HIV01$465.00