3D Structure — Nanobody–Epitope Complex
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anti-Spike protein S2' nanobody complex
PDB 8JVA
■ nanobody (VHH) ■ antigen ■ epitope (19)
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Interactive model of the VHH bound to its structural epitope on Spike protein S2' (from experimental complex PDB 8JVA). Nanobody in blue, epitope contact residues in red. For research visualization.
Product Description
| Product Name | Anti-Spike protein S2' Nanobody (VHH), Recombinant, Purified |
| Description | A purified, engineered single-domain antibody (VHH / nanobody) against Spike protein S2', for research applications including detection, capture and imaging. |
| Target / Specificity | Spike protein S2' |
| Sequence | This nanobody is an engineered variant based on PDB 8JVA, with higher affinity and stability than the original published sequence. |
| Format | Purified recombinant single-domain antibody (VHH / nanobody), carrier-free |
| Tag & Expression | C-terminal 6×His tag; secreted from HEK293 cells and purified by one-step IMAC from the culture medium. |
| Molecular Weight | ~14 kDa (single VHH domain + His6; ~1/10 the size of a conventional IgG) |
| Purity | >90% by SDS-PAGE |
| Quantity | 100 µg |
| Formulation | PBS with 50% glycerol (carrier-free); 0.02% sodium azide |
| Applications | ELISA, Western blot (WB), immunofluorescence (IF), immunoprecipitation (IP), affinity capture |
| Structural Epitope | Epitope mapped from the experimental VHH–antigen complex (PDB 8JVA); 19 antigen contact residues within 5 Å. An interactive 3D complex model is shown on this page. |
| Storage | Store at -20°C; avoid repeated freeze-thaw. Stable 1 year. |
| Advantages | Nanobodies are the smallest functional antibody fragments: exceptional thermal and chemical stability, single-domain, high-yield recombinant production, and access to cryptic epitopes and dense tissue that conventional antibodies cannot reach. |
Product Documents
DatasheetEG-NB-8JVA Product Datasheet
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