Anti-M1 muscarinic acetylcholine receptor Nanobody (VHH), Recombinant, Purified
Catalog #: EG-NB-9UCP
$445.00
3D Structure — Nanobody–Epitope Complex
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anti-M1 muscarinic acetylcholine receptor nanobody complex
PDB 9UCP
■ nanobody (VHH) ■ antigen ■ epitope (31)
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Interactive model of the VHH bound to its structural epitope on M1 muscarinic acetylcholine receptor (from experimental complex PDB 9UCP). Nanobody in blue, epitope contact residues in red. For research visualization.
Product Description
| Product Name | Anti-M1 muscarinic acetylcholine receptor Nanobody (VHH), Recombinant, Purified |
| Description | A purified, engineered single-domain antibody (VHH / nanobody) against M1 muscarinic acetylcholine receptor, for research applications including detection, capture and imaging. |
| Target / Specificity | M1 muscarinic acetylcholine receptor |
| Sequence | This nanobody is an engineered variant based on PDB 9UCP, with higher affinity and stability than the original published sequence. |
| Format | Purified recombinant single-domain antibody (VHH / nanobody), carrier-free |
| Tag & Expression | C-terminal 6×His tag; secreted from HEK293 cells and purified by one-step IMAC from the culture medium. |
| Molecular Weight | ~14 kDa (single VHH domain + His6; ~1/10 the size of a conventional IgG) |
| Purity | >90% by SDS-PAGE |
| Quantity | 100 µg |
| Formulation | PBS with 50% glycerol (carrier-free); 0.02% sodium azide |
| Applications | ELISA, Western blot (WB), immunofluorescence (IF), immunoprecipitation (IP), affinity capture |
| Structural Epitope | Epitope mapped from the experimental VHH–antigen complex (PDB 9UCP); 31 antigen contact residues within 5 Å. An interactive 3D complex model is shown on this page. |
| Storage | Store at -20°C; avoid repeated freeze-thaw. Stable 1 year. |
| Advantages | Nanobodies are the smallest functional antibody fragments: exceptional thermal and chemical stability, single-domain, high-yield recombinant production, and access to cryptic epitopes and dense tissue that conventional antibodies cannot reach. |
Product Documents
DatasheetEG-NB-9UCP Product Datasheet
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