Anti-Complement C5 alpha chain Nanobody (VHH), Recombinant, Purified

Anti-Complement C5 alpha chain Nanobody (VHH), Recombinant, Purified

Catalog #: EG-NB-8CML
$425.00
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3D Structure — Nanobody–Epitope Complex
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anti-Complement C5 alpha chain nanobody complex
PDB 8CML
nanobody (VHH)   antigen   epitope (18)
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Interactive model of the VHH bound to its structural epitope on Complement C5 alpha chain (from experimental complex PDB 8CML). Nanobody in blue, epitope contact residues in red. For research visualization.

Product Description
Product NameAnti-Complement C5 alpha chain Nanobody (VHH), Recombinant, Purified
DescriptionA purified, engineered single-domain antibody (VHH / nanobody) against Complement C5 alpha chain, for research applications including detection, capture and imaging.
Target / SpecificityComplement C5 alpha chain
SequenceThis nanobody is an engineered variant based on PDB 8CML, with higher affinity and stability than the original published sequence.
FormatPurified recombinant single-domain antibody (VHH / nanobody), carrier-free
Tag & ExpressionC-terminal 6×His tag; secreted from HEK293 cells and purified by one-step IMAC from the culture medium.
Molecular Weight~14 kDa (single VHH domain + His6; ~1/10 the size of a conventional IgG)
Purity>90% by SDS-PAGE
Quantity100 µg
FormulationPBS with 50% glycerol (carrier-free); 0.02% sodium azide
ApplicationsELISA, Western blot (WB), immunofluorescence (IF), immunoprecipitation (IP), affinity capture
Structural EpitopeEpitope mapped from the experimental VHH–antigen complex (PDB 8CML); 18 antigen contact residues within 5 Å. An interactive 3D complex model is shown on this page.
StorageStore at -20°C; avoid repeated freeze-thaw. Stable 1 year.
AdvantagesNanobodies are the smallest functional antibody fragments: exceptional thermal and chemical stability, single-domain, high-yield recombinant production, and access to cryptic epitopes and dense tissue that conventional antibodies cannot reach.
Product Documents
DatasheetEG-NB-8CML Product Datasheet
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